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An International MedicReS Initiative

CORE 2027

A Specialty-Based Consensus Project on Clinical Biostatistics Education in Postgraduate Medical Training

From the realities of clinical research to the collective expertise of medical specialties. Defining clinical biostatistics education together.

Implementation in Türkiye is led by KlinBiS.

100 → 300 → 03 → 01CORE / 2027
CORE2027
A shared scientific foundation + the research reality of each specialty
100 Scientific Fields. 300 Scientists. 3 Delphi Rounds. 1 Shared Competency Framework.

The project’s intended scope

100Scientific fields
300Scientists
03Delphi rounds
01Shared competency framework

01 / A SHARED QUESTION

Why CORE 2027?

Clinical research questions, data structures and approaches to generating evidence differ across specialties. Clinical biostatistics education should address these differences on a shared scientific foundation. CORE 2027 aims to define the competencies needed through the experience of the specialties themselves.

Which clinical biostatistics competencies should a specialist physician possess to conduct high-quality clinical research and generate scientific evidence in their own field?

02 / MEDICAL SPECIALTIES

100 Scientific Fields.
Every field has its own research reality.

The project aims to identify research needs across 100 scientific fields. The examples below illustrate how specialty-specific questions can inform a shared framework; the final list of fields and competency sets will be shaped through the consensus process.

01

Cardiology

Risk and clinical outcomes over time

Survival analysis · risk models
02

Oncology

Treatment response and survival

Endpoint selection · treatment effects
03

Paediatrics

Growth, development and follow-up

Repeated measures · age-specific data
04

General Surgery

Comparing outcomes of interventions

Confounding · outcomes research
05

Psychiatry

Measuring clinical change reliably

Scales · measurement validity
06

Radiology

Evaluating diagnostic evidence

Diagnostic accuracy · interobserver agreement

03 / SCIENTIFIC METHOD

From diverse experience to shared consensus.

A five-stage process aims to translate specialty contributions into a competency framework using a Modified Delphi approach.

  1. 01

    Defining the Specialties

    Research contexts and the scope of each field are identified.

  2. 02

    Scientific Panels

    Clinical experience and methodological expertise address a shared question.

  3. 03

    Modified Delphi

    Three rounds of independent assessment, structured feedback and reassessment are conducted.

  4. 04

    Specialty-Specific Competencies

    Priority clinical biostatistics competencies are defined for each field.

  5. 05

    The CORE 2027 Framework

    The common core and specialty-specific sets are integrated.

3-round Modified DelphiConceptual illustration · not outcome data
  1. 01Assessment
  2. 02Feedback
  3. 03Reassessment
300↗

Scientists

04 / SCIENTIFIC PARTICIPATION

Be the Voice of Your Specialty

We aim to bring together the research experience of medical specialties through contributions from approximately 300 scientists. Bring your field’s questions, methodological challenges and educational needs into the process.

Join CORE 2027 To participate, use the existing KlinBiS Network form.

05 / COMPETENCY STRUCTURE

Biostatistics education tailored to each specialty.

A shared scientific foundation is complemented by competencies that reflect research questions, data types and clinical decision-making contexts. The topics below illustrate the proposed structure; the final content will emerge from the consensus process.

Common Core

  • Research design
  • Uncertainty and bias
  • Effect sizes and interpretation
  • Transparent reporting

Specialty-Specific Competencies

  • Specialty-specific endpoints
  • Distinct data structures
  • Appropriate analytical methods
  • Evidence in clinical context
CORE 2027 Competency Framework

A shared scientific foundation + the research reality of each specialty

06 / EXPECTED OUTPUTS

What Will We Produce?

CORE 2027TÜRKİYE

  1. 01Research needs identified across 100 scientific fields
  2. 02Structured contributions from approximately 300 scientists
  3. 03Competencies assessed through 3 Delphi rounds
  4. 04A common core of clinical biostatistics competencies
  5. 05Specialty-specific competency sets
  6. 06A scientific framework to inform educational content
  7. 07The CORE 2027 Türkiye Results Report

07 / IN THE AGE OF AI

Tools Change. Scientific Responsibility Remains.

Artificial intelligence can accelerate research and analysis. Yet formulating the right question, evaluating study design, examining assumptions and interpreting findings in clinical context require scientific competence. CORE 2027 aims to establish an educational framework that sustains this responsibility beyond the use of any particular tool.

  • The right research question
  • Methodological appraisal
  • Critical interpretation
  • Scientific responsibility

08 / ROADMAP

From 2026 to 2027.

Planned scientific process

  1. Structure and panels

    Defining specialties and establishing scientific panels.

  2. Delphi process

    Three rounds of assessment, feedback and competency development.

  3. Istanbul

    The first scientific findings are planned to be shared.

    2027 Congress
  4. Results report and framework

    Preparation of the CORE 2027 Türkiye Results Report and competency framework.

CORE 2027 / SHAPING THE FRAMEWORK TOGETHER

Bring Your Specialty’s Research Reality to CORE 2027.

Let your field’s experience help shape the future of clinical biostatistics education.

Join CORE 2027
An International MedicReS InitiativeImplementation in Türkiye is led by KlinBiS.